Cincinnati Open 1981
John McEnroe won the title, beating Chris Lewis 6–3 6–4 in the final.
Main draw 64 players
- 1🇺🇸John McEnroeFinal · Champion
- 2🇺🇸Jimmy ConnorsRound of 16 · Lost to Vitas Gerulaitis
- 3🇺🇸Gene MayerRound of 64 · Lost to Bruce Manson
- 4🇺🇸Roscoe TannerRound of 16 · Lost to Thierry Tulasne
- 5🇺🇸Brian TeacherRound of 32 · Lost to Raul Ramirez
- 7🇺🇸Harold SolomonRound of 32 · Lost to Rick Fagel
- 8🇫🇷Yannick NoahRound of 64 · Lost to Tim Gullikson
- 9🇺🇸Vitas GerulaitisQuarterfinals · Lost to Stan Smith
- 10🇺🇸Brian GottfriedRound of 16 · Lost to John McEnroe
- 11🇺🇸John SadriRound of 64 · Lost to Chris Lewis
- 12🇺🇸Bob LutzQuarterfinals · Lost to John McEnroe
- 13🇮🇳Vijay AmritrajRound of 64 · Lost to Bill Scanlon
- 14🇨🇿Tomas SmidRound of 16 · Lost to Raul Ramirez
- 15🇺🇸Victor AmayaRound of 32 · Lost to Thierry Tulasne
- 16🇺🇸Stan SmithSemifinals · Lost to Chris Lewis
- 🇳🇿Chris LewisFinal · Lost to John McEnroe
- 🇲🇽Raul RamirezSemifinals · Lost to John McEnroe
- WC🇺🇸Bill ScanlonQuarterfinals · Lost to Chris Lewis
- 🇫🇷Thierry TulasneQuarterfinals · Lost to Raul Ramirez
- 🇫🇷Christophe Roger-VasselinRound of 16 · Lost to Chris Lewis
- Q🇳🇬Nduka OdizorRound of 16 · Lost to Bill Scanlon
- 🇺🇸Rick FagelRound of 16 · Lost to Bob Lutz
- 🇺🇸Tim GulliksonRound of 16 · Lost to Stan Smith
- 🇺🇸Bruce MansonRound of 32 · Lost to Nduka Odizor
- 🇵🇾Francisco GonzalezRound of 32 · Lost to Bob Lutz
- 🇷🇴Ilie NastaseRound of 32 · Lost to Christophe Roger-Vasselin
- Q🇫🇷Jerome PotierRound of 32 · Lost to Roscoe Tanner
- 🇺🇸Jimmy AriasRound of 32 · Lost to Tim Gullikson
- 🇺🇸John AustinRound of 32 · Lost to Vitas Gerulaitis
- 🇺🇸Kevin CurrenRound of 32 · Lost to Tomas Smid
- 🇺🇸Lloyd BourneRound of 32 · Lost to Brian Gottfried
- Q🇺🇸Marcel FreemanRound of 32 · Lost to Stan Smith
- Q🇺🇸Mike CahillRound of 32 · Lost to John McEnroe
- 🇮🇳Ramesh KrishnanRound of 32 · Lost to Bill Scanlon
- 🇿🇦Raymond MooreRound of 32 · Lost to Chris Lewis
- 🇳🇿Russell SimpsonRound of 32 · Lost to Jimmy Connors
- 🇨🇴Alejandro CortesRound of 64 · Lost to Bob Lutz
- 🇿🇦Bernie MittonRound of 64 · Lost to Roscoe Tanner
- 🇦🇺Brad DrewettRound of 64 · Lost to Ilie Nastase
- 🇺🇸Craig WittusRound of 64 · Lost to Francisco Gonzalez
- 🇺🇸Curt StalderRound of 64 · Lost to Thierry Tulasne
- Q🇺🇸David DowlenRound of 64 · Lost to Brian Teacher
- 🇫🇷Dominique BedelRound of 64 · Lost to Russell Simpson
- 🇺🇸Erik Van DillenRound of 64 · Lost to Tomas Smid
- 🇺🇸Ferdi TayganRound of 64 · Lost to Raul Ramirez
- 🇮🇹Gianni OcleppoRound of 64 · Lost to Victor Amaya
- 🇸🇪Jan NorbackRound of 64 · Lost to Vitas Gerulaitis
- 🇺🇸Jeff BorowiakRound of 64 · Lost to Jerome Potier
- 🇦🇺John FitzgeraldRound of 64 · Lost to Mike Cahill
- Q🇺🇸Kevin KernsRound of 64 · Lost to John Austin
- LL🇺🇸Larry StefankiRound of 64 · Lost to Christophe Roger-Vasselin
- 🇦🇺Mark EdmondsonRound of 64 · Lost to Brian Gottfried
- 🇺🇸Nick SavianoRound of 64 · Lost to Nduka Odizor
- WC🇫🇷Pascal PortesRound of 64 · Lost to Stan Smith
- 🇺🇸Pat DupreRound of 64 · Lost to Harold Solomon
- Q🇿🇦Paul AvisRound of 64 · Lost to Raymond Moore
- 🇸🇪Per HjertquistRound of 64 · Lost to Ramesh Krishnan
- 🇦🇹Peter FeiglRound of 64 · Lost to Rick Fagel
- 🇺🇸Sherwood StewartRound of 64 · Lost to Marcel Freeman
- 🇮🇱Shlomo GlicksteinRound of 64 · Lost to John McEnroe
- 🇺🇸Tom GulliksonRound of 64 · Lost to Jimmy Arias
- Q🇺🇸Tracy DelatteRound of 64 · Lost to Kevin Curren
- 🇺🇸Trey WaltkeRound of 64 · Lost to Lloyd Bourne
- 🇺🇸Van WinitskyRound of 64 · Lost to Jimmy Connors